Ampicillin Nursing Considerations, Side Effects and Mechanism of Action Pharmacology for Nurses

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Ampicillin

Generic Name: ampicillin

Trade Name: Principen

Indication: skin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia

Action: bactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death

Therapeutic Class: anti-infective

Pharmacologic Class: aminopenicillin

Nursing Considerations
 contraindicated in penicillin allergy, use caution in renal insufficiency
 may lead to seizures, diarrhea, anaphylaxes, super infection
 assess for infection
 monitor liver function tests
 instruct patient on signs of super infection: fury over growth on tongue, vaginal itching, loose and foul smelling stool
 pt should not use with oral contraceptive use.

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